Sanaxeen is a treatment against lower urinary tracts symptoms (LUTS) based on a standardised pollen extract. Micturation is dependent on the integrity of a complex neuromuscular network in the lower urinary tract. Any disturbance in this network in the bladder and urethra will lead to micturation dysfunction. Symptoms related to micturation dysfunction are called LUTS. These symptoms could be the need of visiting the toilet frequently both during the day and night, dribbling, poor flow, incomplete emptying etc.

The most common cause behind LUTS is benign prostatic hyperplasic (BPH). Around the age of fourty-five, the prostate tends to become larger causing the narrowing of the urinary tract that passes through the gland. Pollen extracts have been used as a treatment of benign prostatic hyperplasic (BPH) for more than forty years. Several clinical studies since then confirm that pollen treatment gives significant improvement when it comes to problems and symptoms caused by BPH.

There are foremost two areas where the pollen extracts and thereby Sanaxeen has a positive effect on problems caused by BPH; namely the effect on the bladder and the urethra.

1. The detrusor muscle, a muscle that helps emptying the bladder, reacts to the pollen extracts by activating the muscarin receptors in the detursor muscle. This strengthens the muscle and helps emptying of the bladder completely. Further studies confirmed that the pollen extract significantly affects the pressure inside the bladder which also facilitates emptying of the bladder.

2. Furthermore the extracts affect the muscles in the urethra by preventing contractions caused by noradrenalin. The passage through the urethra is kept open which makes urinating easier.